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Section: Partnerships and Cooperations
International Initiatives
Informal International Partners
Collaboration with Max-Planck Institute, Martinsried (Germany), Dr. Julio Ortiz and Antonio Martinez: Detection and segmentation of macromolecules in cryo-electron tomography (project in progress with Emmanuel Moebel and Charles Kervrann).
Inria Associate Teams Not Involved in an Inria International Labs
CytoDI Inria Associated-Team
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See also: http://serpico.rennes.inria.fr/doku.php?id=research:cytodi
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Participants: Sandeep Manandhar, Patrick Bouthemy, Charles Kervrann.
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The main scientific goal of the Associated-Team is the spatiotemporal characterization and comparison of cytoskeleton networks involved in cell migration and observed through live cell imaging in three dimensions (3D). Those networks include the cytoskeleton, i.e., microtubules (MT), intermediate filaments (IF), dynamically resolvable by Bessel Beam Light Sheet fluorescent microscopy. The goal will be achieved through the design of local and global descriptors of the spatial conformation and deformation of the cytoskeleton. Subsequently, general metrics to compare and classify the MT and IF networks will be investigated. This study will be carried out on oncogenically transformed lung cancer epithelial cells.
In 2018, the objective of the visit of Sandeep Manandhar (PhD student) at UTSW Dallas (March 1-31, 2018) was to i) get a deeper understanding of bioimaging capacities and limitations in the context of biological studies, 2) to refine the design and validation of his approaches in this context and 3) returning from his visit with a clear vision for biologically relevant tools. For the Danuser lab, the objective was 1) to evaluate the breakpoint of path-match-based approach toward heterogeneous motion 2) to fill the gap between object tracking and generic motion estimation for studies such as actin speckle or collagen.